(Reuters) – Merck & Co said on Tuesday its blockbuster therapy Keytruda used along with chemotherapy failed to meet the main goals of a late-stage study testing the combination as a first-line treatment for bladder cancer.
The trial did not meet the main goals of overall survival or progression-free survival, compared with standard-of-care chemotherapy alone, the company said in a statement.
The company said Keytruda helped improve overall survival and progression-free survival, but failed to achieve statistical significance.
Keytruda, which brought in sales of $ 3.28 billion in the first quarter, has already received three U.S. regulatory approvals for different types of bladder cancers.
In January, the U.S. Food and Drug Administration approved reut.rs/2MKHASF Keytruda for a hard-to-treat form of bladder cancer, making it the first new treatment for the cancer in more than two decades.
Reporting by Trisha Roy in Bengaluru; Editing by Devika Syamnath