Stewart DE, Vigod SN. Annu Rev Med. 2019 Jan 27;70:183-196.
Sharma V, Bergink V, Berk M, Chandra PS, Munk-Olsen T, Viguera AC, Yatham LN. Lancet Psychiatry. 2019 Sep;6(9):786-792.
The authors describe the clinical characteristics of women at risk of developing bipolar disorder after childbirth, before discussing opportunities for prevention and early intervention and outlining challenges in the assessment and management of women at risk of transitioning to bipolar disorder after childbirth. Existing evidence, although scarce, supports a clinical staging model by which at-risk women are managed with a variety of behavioural and pharmacological interventions aimed at preventing bipolar disorder.
Perry A, Gordon-Smith K, Webb I, Fone E, Di Florio A, Craddock N, Jones I, Jones L. BMC Psychiatry. 2019 Dec 12;19(1):395. Free Article
Personality traits, cognitive styles and affective temperaments previously shown to be associated with bipolar disorder in general were not specifically associated with the occurrence of postpartum psychosis.
Wajid A, Kingston D, Bright KS, Kashif Mughal M, Charrois EM, Giallo R. J Affect Disord. 2019 Nov 30;263:31-38.
Researchers identified five distinct trajectories of maternal psychological distress symptoms over time. Predictors of trajectories with elevated symptoms reflected a pattern of social and economic disadvantage and psychosocial stress. The strongest predictors of elevated mental health symptoms were a history of depression [OR: 7.57(4.73-12.11)] and 3 or more stressful life events in the past year [OR: 3.38(2.02-5.65)].
Wang J, Yun Q, Ma SF, Song HR, Guo MN, Zhang WN. Biochem Biophys Res Commun. 2019 Dec 11.
In a rat model of PPD, reduced expression of gonadotropin receptors was was observed in the hippocampus.
Gelabert E, Gutierrez-Zotes A, Navines R, Labad J, et al. Arch Womens Ment Health. 2019 Dec 4
Seven percent of mothers reported suicidal ideation during the first 8 months postpartum. Sixty-two percent of women with suicidal ideation had a major depressive episode at 8 weeks, and 70% at 32 weeks postpartum.